| wednesday december 23 - 02:46 |  Medellin #4 [15] | 3-0 | Barranquilla [12] |
| wednesday december 23 - 09:39 | Quibdó [3] | 1-0 | Los Lobos [9] |
| wednesday december 23 - 11:46 | Sogamoso #2 [11] | 4-0 | Barranquilla #2 [8] |
| wednesday december 23 - 13:51 | Puerto Berrío [4] | 0-5 | Pamplona #2 [9] |
| wednesday december 23 - 14:28 | Buga #2 [0] | 0-1 | Bucaramanga #2 [7] |
| wednesday december 23 - 17:49 | Villavicencio fútbol club [4] | 2-2 | Medellín [7] |
| wednesday december 23 - 18:32 | Cartago [9] | 2-1 | El Cerrito [9] |
| wednesday december 23 - 19:18 | Fusagasugá [4] | 3-0 | Girón #2 [0] |
| wednesday december 23 - 19:20 | Ibagué #6 [10] | 2-2 | Cali #3 [9] |
| wednesday december 23 - 19:34 | Bogota #3 [3] | 0-0 | Florencia #2 [7] |
