| الاثنين جانفي 21 - 05:48 |  AS Afragola #2 [58] | 0-4 | AC Valdinievole [24] |
| الاثنين جانفي 21 - 06:25 | AC Ascoli Piceno #2 [48] | 2-4 | AS Florence #3 [42] |
| الاثنين جانفي 21 - 08:41 | AC Reggio nell'Emilia #2 [51] | 2-5 | AS Cagliari #3 [61] |
| الاثنين جانفي 21 - 08:46 | FC Empoli [51] | 2-2 | AC Perugia #3 [47] |
| الاثنين جانفي 21 - 10:19 | Crotone [68] | 1-5 | Giugliano in Campania FC #2 [59] |
| الاثنين جانفي 21 - 11:16 | AC Rimini #2 [41] | 0-1 | Brescia #5 [17] |
| الاثنين جانفي 21 - 13:40 | AC Reggio di Calabria #2 [65] | 2-4 | AC Imola [68] |
| الاثنين جانفي 21 - 16:21 | AS Sesto San Giovanni [29] | 0-2 | AS Milan [51] |
| الاثنين جانفي 21 - 16:46 | Foggia [62] | 1-3 | AS Fiumicino [27] |
| الاثنين جانفي 21 - 20:39 | Milan #10 [57] | 2-1 | AC Rome #7 [57] |
