| tirsdag september 15 - 06:45 |  ⭐ PSV Eindhoven ⭐ [17] | 3-0 | SC Heusden [13] |
| tirsdag september 15 - 09:22 | FC Wijchen [13] | 1-1 | SC Middelburg [9] |
| tirsdag september 15 - 09:43 | FC New Buitenpost [10] | 0-0 | SC Steenwijk [11] |
| tirsdag september 15 - 13:22 | SC Den Helder [3] | 1-1 | Feyenoord [12] |
| tirsdag september 15 - 17:46 | FC Bergen NH [4] | 2-0 | FC Goor [12] |
| tirsdag september 15 - 17:47 | **** The Hague FC **** [10] | 0-1 | SC De Bilt [3] |
| tirsdag september 15 - 17:48 | SC Genemuiden [6] | 0-3 | JSV-Players [14] |
| tirsdag september 15 - 19:24 | FC Black Rose [14] | 0-1 | NextGen FC [10] |
| tirsdag september 15 - 19:44 | SC Cambuur [4] | 3-1 | Manchester United H [6] |
