| onsdag april 6 - 14:20 |  Real Sestao #2 [6] | 3-0 | Aqvinos [3] |
| onsdag april 6 - 14:51 | FC Fuenlabrada #2 [13] | 4-0 | Atletico Oleiros [4] |
| onsdag april 6 - 16:50 | Castelló de la Plana #5 [10] | 3-0 | FC Alcorcón #4 [0] |
| onsdag april 6 - 18:25 | RCR Tartessos [9] | 0-1 | Cinturones Fucsias [13] |
| onsdag april 6 - 18:28 | Euskalduna [14] | 4-1 | Atletico Santander [8] |
| onsdag april 6 - 18:34 | Real Valladolid [16] | 1-3 | FC Tortosa #2 [9] |
| onsdag april 6 - 19:15 | Atletico Getafe #2 [6] | 0-5 | Jozemi CF [7] |
| onsdag april 6 - 19:21 | Alcantarilla #2 [6] | 2-0 | Atletico Guadalajara #2 [0] |
| onsdag april 6 - 19:22 | CDPapagai [7] | 2-1 | Sporting de Coru [13] |
| onsdag april 6 - 19:26 | Arandina C F [14] | 0-0 | Real Málaga [15] |
