| tisdag december 23 - 02:25 |  Monterrey [3] | 1-1 | MXL Guajos University [6] |
| tisdag december 23 - 02:27 | MXL The Red Devils 1878 [3] | 1-3 | America [7] |
| tisdag december 23 - 04:26 | Leon [4] | 5-0 | Nezahualcóyotl [1] |
| tisdag december 23 - 04:50 | Puebla #2 [1] | 1-1 | Querétaro [1] |
| tisdag december 23 - 06:36 | Jalapa Enríquez [1] | 1-3 | MXL Marin [9] |
| tisdag december 23 - 14:20 | México City [6] | 1-2 | Poza Rica de Hidalgo [9] |
| tisdag december 23 - 16:47 | Valle de Chalco [3] | 1-3 | Reynosa #2 [6] |
| tisdag december 23 - 17:21 | MXL Xicuahua [6] | 1-3 | MXL Luneng Taishan [9] |
| tisdag december 23 - 22:47 | Mexicali [0] | 0-5 | MXL Inter mgls FC [2] |
