| tuesday december 18 - 01:33 |  Los Ángeles [4] | 0-2 | Con Con National [7] |
| tuesday december 18 - 13:48 | Cultural-Obrero [1] | 0-0 | Valparaíso [6] |
| tuesday december 18 - 17:15 | Copiapó [4] | 3-0 | Viña del Mar #2 [9] |
| tuesday december 18 - 17:30 | Arica [7] | 1-0 | Everton de Viña de Mar [9] |
| tuesday december 18 - 17:36 | Puerto Montt [1] | 3-5 | Castro [9] |
| tuesday december 18 - 17:49 | La Serena #3 [0] | 2-2 | Coronel [4] |
| tuesday december 18 - 20:16 | Talca #2 [6] | 3-1 | Red Bull NextGen [2] |
| tuesday december 18 - 20:22 | General Velásquez FC [1] | 4-2 | Colina [0] |
| tuesday december 18 - 22:16 | Puente Alto #2 [3] | 1-1 | FC Spartacus [3] |
