| friday december 18 - 02:35 |  San Juan Nepomuceno [0] | 0-1 | Cali #18 [3] |
| friday december 18 - 04:39 | Santa Marta #7 [0] | 0-1 | Medellin #16 [0] |
| friday december 18 - 05:15 | Medellin #19 [0] | 0-0 | Barrancabermeja #6 [0] |
| friday december 18 - 13:44 | Soacha #3 [3] | 3-1 | Sogamoso #3 [1] |
| friday december 18 - 14:45 | Roldanillo [1] | 0-1 | Bogota #22 [1] |
| friday december 18 - 17:45 | Barranquilla #11 [0] | 0-2 | Caldas #2 [3] |
| friday december 18 - 18:50 | Cúcuta #8 [0] | 4-1 | Valledupar [0] |
| friday december 18 - 18:50 | Sincelejo #3 [1] | 3-1 | Montería #5 [3] |
| friday december 18 - 19:40 | Caicedonia [3] | 3-1 | Cali #19 [3] |
| friday december 18 - 20:38 | Tulúa #3 [3] | 2-3 | Pradera [3] |
