| wednesday june 26 - 02:24 |  Caldas #2 [2] | 0-2 | El Bagre [36] |
| wednesday june 26 - 04:32 | Domzale FC [95] | 3-0 | selección santander [74] |
| wednesday june 26 - 06:34 | Independiente Medellín [42] | 0-3 | Medellin #12 [87] |
| wednesday june 26 - 13:15 | Cúcuta #6 [33] | 3-1 | Anserma [9] |
| wednesday june 26 - 13:35 | AVALANCHA AZUL [19] | 1-0 | Girón #2 [30] |
| wednesday june 26 - 18:19 | Esfinge fc [71] | 3-0 | Los Potrillos [43] |
| wednesday june 26 - 18:24 | Toros de Letonia [78] | 3-0 | Montenegro [32] |
| wednesday june 26 - 19:36 | fc atletico verdolaga [57] | 2-0 | Real Soacha Cundinamarca [47] |
| wednesday june 26 - 20:34 | Castores Yaguara [64] | 2-0 | Kanda fc [26] |
| wednesday june 26 - 22:50 | Junior FC [79] | 2-0 | Deportivo Dynamo [65] |
