| wednesday november 25 - 01:32 |  San José de la Lajas [8] | 0-11 | Dracena Melilla FC [75] |
| wednesday november 25 - 01:38 | Avileño United [16] | 1-4 | Camagüey #3 [37] |
| wednesday november 25 - 09:43 | Havana Granata [15] | 0-10 | Holguín [45] |
| wednesday november 25 - 11:49 | Cuban Rum [64] | 5-0 | Matanzas [44] |
| wednesday november 25 - 13:30 | Bzbc FC [60] | 0-0 | Neptuni pediludium [70] |
| wednesday november 25 - 13:50 | Havana #7 [1] | 0-11 | Cienfuegos #2 [76] |
| wednesday november 25 - 19:27 | Sagua la Grande [31] | 9-0 | Santa Cruz del Sur [10] |
| wednesday november 25 - 19:27 | Guantánamo [52] | 1-1 | Puerto Padre [32] |
