| wednesday june 23 - 01:35 |  Avileño United [24] | 0-3 | Sagua la Grande [31] |
| wednesday june 23 - 09:29 | Matanzas [49] | 1-0 | Camagüey #3 [32] |
| wednesday june 23 - 11:15 | Neptuni pediludium [75] | 1-4 | Prince of Rome [85] |
| wednesday june 23 - 13:41 | Havana #7 [5] | 4-1 | Güines [1] |
| wednesday june 23 - 13:43 | Bzbc FC [55] | 4-0 | Holguín [53] |
| wednesday june 23 - 19:51 | Guantánamo [64] | 1-3 | Cuban Rum [73] |
| wednesday june 23 - 20:20 | Dracena Melilla FC [76] | 13-0 | San José de la Lajas [18] |
| wednesday june 23 - 22:45 | Havana #10 [7] | 0-6 | Puerto Padre [38] |
