| friday october 28 - 04:49 |  Estrellado [6] | 2-0 | San Vicente [2] |
| friday october 28 - 11:30 | CS Emelec [1] | 3-0 | Defensores V Ramallo [4] |
| friday october 28 - 13:30 | Guaymallén [4] | 2-2 | Catamarca [7] |
| friday october 28 - 13:31 | La Matanza #2 [7] | 0-3 | Rosario Leprosa [4] |
| friday october 28 - 13:42 | C A Timbuense [3] | 1-0 | Belén de Escobar #3 [5] |
| friday october 28 - 17:23 | José Carlos Paz [2] | 1-0 | El Colmenar #2 [5] |
| friday october 28 - 17:46 | River Plate - San Luis [1] | 2-0 | Charata [1] |
| friday october 28 - 19:48 | Empoli FC [2] | 2-0 | Unixon [9] |
| friday october 28 - 20:38 | B0ca jun10rs [4] | 3-1 | Buenos Aires #4 [6] |
| friday october 28 - 20:50 | Cordoba #5 [3] | 3-0 | San Miguel [4] |
