| tuesday december 22 - 01:39 |  Los Lobos [6] | 1-0 | Puerto Berrío [4] |
| tuesday december 22 - 08:30 | El Cerrito [6] | 2-0 | Bogota #3 [3] |
| tuesday december 22 - 14:19 | Cali #3 [6] | 2-1 | Fusagasugá [4] |
| tuesday december 22 - 14:27 | Medellín [4] | 2-1 | Buga #2 [0] |
| tuesday december 22 - 14:41 | Barranquilla [9] | 2-0 | Quibdó [3] |
| tuesday december 22 - 14:43 | Florencia #2 [7] | 1-2 | Ibagué #6 [7] |
| tuesday december 22 - 17:21 | Bucaramanga #2 [6] | 0-0 | Cartago [8] |
| tuesday december 22 - 17:48 | Girón #2 [0] | 0-7 | Medellin #4 [12] |
| tuesday december 22 - 20:18 | Pamplona #2 [8] | 1-1 | Sogamoso #2 [10] |
| tuesday december 22 - 20:40 | Barranquilla #2 [5] | 2-0 | Villavicencio fútbol club [4] |
