| friday december 18 - 02:22 |  La Plata FC [0] | 1-2 | San Miguel [3] |
| friday december 18 - 02:23 | Chilecito [3] | 2-2 | Trelew [3] |
| friday december 18 - 11:38 | Club Atlético Tigre [0] | 3-1 | Pilar #2 [3] |
| friday december 18 - 11:46 | Deportivo Riestra [0] | 2-3 | Sparta Buenos Aires [0] |
| friday december 18 - 14:28 | Quilmes #3 [0] | 1-0 | La Matanza #2 [3] |
| friday december 18 - 14:31 | Catamarca [0] | 2-1 | B0ca jun10rs [3] |
| friday december 18 - 16:51 | Berazategui #3 [0] | 4-1 | Cordoba #5 [0] |
| friday december 18 - 17:19 | River Plate - San Luis [3] | 1-1 | Victoria [3] |
| friday december 18 - 17:23 | José Carlos Paz [0] | 1-0 | Caucete #2 [0] |
| friday december 18 - 19:19 | Empoli FC [3] | 2-1 | El Colmenar #2 [3] |
