| monday december 21 - 02:24 |  La Plata FC [0] | 0-1 | La Matanza #2 [6] |
| monday december 21 - 02:46 | Chilecito [4] | 1-2 | Mar del Plata [6] |
| monday december 21 - 11:25 | Deportivo Riestra [1] | 3-0 | Cordoba #5 [1] |
| monday december 21 - 14:15 | Catamarca [3] | 0-0 | Trelew [7] |
| monday december 21 - 14:23 | Quilmes #3 [6] | 3-2 | El Colmenar #2 [4] |
| monday december 21 - 16:44 | Berazategui #3 [4] | 0-1 | B0ca jun10rs [3] |
| monday december 21 - 17:21 | José Carlos Paz [3] | 1-0 | Pilar #2 [6] |
| monday december 21 - 17:33 | River Plate - San Luis [7] | 2-2 | Caucete #2 [3] |
| monday december 21 - 19:50 | Empoli FC [7] | 1-1 | Victoria [5] |
| monday december 21 - 22:45 | San Miguel [6] | 2-1 | Sparta Buenos Aires [3] |
